Replication Termination: Mechanism of Polar Arrest Revealed
نویسنده
چکیده
The Tus-Ter protein-DNA complex of Escherichia coli blocks progression of DNA replication from only one direction at the replication terminus. As the replication fork helicase unwinds one side of Ter, a conserved cytosine flips out of the duplex and binds to Tus, thereby creating a locked complex that blocks the advancing helicase.
منابع مشابه
Replication termination mechanism as revealed by Tus-mediated polar arrest of a sliding helicase.
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ورودعنوان ژورنال:
- Current Biology
دوره 16 شماره
صفحات -
تاریخ انتشار 2006